Big Flash Project for Desktop

I am wondering if i should run into any problems developing my Flash game for desktop if i want dimensions that are about 800 X 600. I have quite large backgrounds and realize that i'll have to optimize by converting many areas into tiles. Is this the correct way to  go? Some objects will be tweened with small child sprites that animate - to avoid creating huge sprite sheets.
Can anyone tell me how well a game / interactive adventure should run on desktop as a Flash export.
Thanks

What do you mean by desktop as a flash export? Have you already created the game in flash? Desktop runs much faster than flash so you shouldn't need to optimise much.