Ok, you're right...Image quality is good with the asset only at 1x. But with a 10x15 tiles scene, the image is shifted to the left even with camera follow to center.
To center, i need to increase the width of the scene (10 x 21 instead of 10 x 15) and then, i use camera follow to center, and it works perfectly.
The only negative point with scale to fit(full screen), is that everything is smaller on screen!!!
(
Thanks you for your help